Autopsy In A Case Of Severe Malaria (Plasmodium Falciparum)
OPENING A PANDORA`S BOX OF SALIENT MALARIAL PATHOPHYSIOLOGY
Keywords:
Plasmodium falciparum, cerebral malaria, severe malaria, DIC in malaria
Abstract
Malaria is a potentially lethal infectious disease caused by a unicellular protozoan parasite, Plasmodium, transmitted by female Anopheles mosquito (1). Severe malaria, by Pl. falciparum has high mortality rate and is a major cause of death due to malaria (2). As complete pathological autopsies are scarce in India, findings of disseminated malaria are rarely well documented. We report a 36yr old male from non-endemic area with a work station in Bihar, endemic for Pl. falciparum; who died of severe malaria with MODS. Diagnosis was based on history provided, very eminent autopsy table findings and classic histopathological examination findings
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References
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2. Dept of FM & Medicolegal, Faculty of Medicine, University of Riau, Pekanbaru, Indonesia
3. British Committee for Standards in Haematology: The laboratory diagnosis of malaria. Clin Lab Haem.1997;19:165-70
4. Chatterjee KD. Parasitology(Protozoology and Helminthology). 9th Edition. Calcutta. Published by the author. 1973.
5. World Health Organization. New perspectives in malaria diagnosis. World Health Organization. 2000.Geneva,Switzerland. WHO/MAL/2000.1091.
6. Nadjam B, Behrens RH. Malaria: An update for physicians. Infect Dis Clin N Am.2012;26:243-259.
7. Turner GD, Morrison H, Jones M, Davis TM et al. An immunohistochemical study of the pathogenesis of malaria. Evidence for widespread endothelial activation and a potential role for intracellular adhesion molecule-I in cerebral sequestration. Am J Pathol. 1994;145:1057-1069.
8. Baheh R. Laddha P, Gehcot RS. Liver involvement in falciparum malaria-a histopathological analysis. JIACM.2003;4(1):34-8.
9. N and N, Aggarwal H, Sharma M, Singh M. Systemic manifestations of malaria. JIACM.2001;2(3):184-94
10. Laishram DD, Sutton PL Nanda N, et al. The complexities of malarial disease manifestations with a focus on asymptomatic malaria. Malar J 2012;11:29(PubMed).
Published
2025-06-17
How to Cite
1.
Syed S, Shah S, Rasool Z, Ali S, Murtaza H, Saarim S. Autopsy In A Case Of Severe Malaria (Plasmodium Falciparum). jms [Internet]. 2025Jun.17 [cited 2026Oct.14];28(2):49-2. Available from: http://sbe.jmsskims.org/index.php/jms/article/view/1439
Section
Case Reports
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